Company teardown · Latent Labs

Twelve people shipped an AI that writes new proteins. The trick wasn't the AI. It was the wet lab.

Latent Labs shipped its first protein-design model with twelve staff, and an agent that runs whole antibody campaigns with seventeen. The founder co-wrote AlphaFold2; his first hire was a core engineer on AlphaFold 1, 2 and 3. But the telling move was hiring a lab scientist sixteen months before there was a model, so every design the AI guessed got tested, and every test taught the next model. We read the profiles of 26 of its 27 employees, three technical reports and four founder interviews. This is the story the profiles tell.

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Founded
Mid-2023 · London, lab in San Francisco
Team
27 people · 26 read · 14 joined in 2026
Raised
$50M · Radical & Sofinnova · Feb 2025
Models
Latent-X · X2 · the Latent-Y agent
Sells
Platform access to pharma and biotech

0.1 — The whole story · start dates from 26 current profiles and three departures

Eight people after eighteen months. Fourteen in December 2025. Twenty-seven today, half of them hired this year.

8
People, mid-2023 – end of 2024
A founder, an AlphaFold engineer, an operator and a wet lab. No model yet.
14
People in December 2025
$50 million, then two models in five months. The bench is hired from the field's own labs.
26
Profiles read, October 2026, of 27
Fifteen starts and three departures in ten months. The scale year.
Oct 2023
Hire #1: Alex Bridgland, a core engineer on AlphaFold 1, 2 and 3.
Mar 2024
A wet lab in San Francisco, sixteen months before the first model.
Feb 2025
Out of stealth with $50M. Nine people.
Jul 2025
Latent-X ships. Twelve people.
Dec 2025
Latent-X2: the turn to antibodies. Fourteen.
Mar 2026
Latent-Y ships. Around it, two of its authors leave, one back to DeepMind.
May 2026
A Head of AI from Google DeepMind: the founder's collaborator since 2017.
Sep 2026
The talent lead leaves for a competitor. Twenty-seven people by October.

— The 26 profiles read, by the year they joined

Everything here is public: LinkedIn, the company's team page, three technical reports, four founder appearances and the funding press. The reading is ours.

0.2 — A two-minute primer · skip if you know what a binder is

It writes new proteins to order, then checks in its own lab that they stick.

— Read · AlphaFold

A protein is a chain of amino-acid letters folded into a shape, and the shape is the job. Letters in, shape out: a fifty-year problem, and the 2024 Nobel, shared with David Baker.

— Write · Latent

The inverse. Start from a target's shape and invent letters that fold into a key for it. Shape in, letters out. The key is called a binder; antibodies are the body's own.

01 · Design

Grip the pocket Take a disease protein, say one on a tumour cell, with a pocket nothing in the body fits. The model writes new proteins shaped to grip it: under a hundred candidates per target, most of them wrong.
→

02 · Make and test

In a real lab The San Francisco wet lab builds the candidates as real molecules and measures which ones actually stick. The results train the next model.
→

03 · Result

67% of targets got a lab-confirmed binder in the Latent-Y runs: a whole antibody campaign from one text prompt.

Sold as software: pharma partners log into the platform, name a target and keep the drug. Latent sells the models and the lab, not medicines.

§ 01 — Part one of four · The spinout · 2023 to 2024

One AlphaFold author left DeepMind. One joined him.

December 2022 to December 2024. A founder, a first hire, a wet lab before there was a model, and eight people by the end of the second year.

1.1 — The founder · Simon Kohl

A physicist who built AlphaFold2's confidence score, then started DeepMind's protein-design team on his own.

2010 – 2019
Karlsruhe and Heidelberg. Physics at KIT, then a KIT computer-science PhD done at the German Cancer Research Center: nnU-Net, and the Probabilistic U-Net as first author at NeurIPS 2018. In 2017 he co-founded the Heidelberg AI meetup with a labmate, Paul Jaeger. Remember the name.
2019 – 2021
DeepMind · AlphaFold2. Research scientist from January 2019, co-author on AlphaFold2 and the AlphaFold database. His part was the confidence head: “It gives you a confidence estimate that we showed is well-calibrated.”
2021 – 2022
DeepMind · Protein design. “First that was just me, then we grew a team around it. I ended up co-leading that team.” Joint team lead until December 2022. AlphaProteo, DeepMind's 2024 binder-design model, came out of that team.
Dec 2022 – Jul 2023
The spinout. Leaves DeepMind at the end of 2022; incorporates Latent Labs in London in mid-2023. The pitch against staying: “I was really keen on running this at incredible speed and then also building a platform around it.”

About 56,000 citations, mostly AlphaFold2. The founding story is the one Isomorphic, Inherent and other London labs tell. A DeepMind lineage and a reason to be faster than DeepMind. What distinguishes them is who they hire next.

1.2 — The first six hires · October 2023 to August 2024

Two from DeepMind, a wet lab in San Francisco, and an antibody modeller long before the antibody model.

01
Alex Bridgland
Founding MTS · October 2023
Nearly six years a DeepMind research engineer; on AlphaFold 1, 2, Multimer and 3. The one AlphaFold engineer the founder brought.
02
Annette Obika Mbatha
Head of Operations · January 2024
Seven and a half years at DeepMind. The second DeepMind hire ran operations, not models.
03
David Yuan
Head of Screening Platform · March 2024 · SF
A lab scientist, lately at Zymergen and Mammoth. The wet lab started sixteen months before the first model.
04
Jonathan Crabbé
MTS · April 2024
Cambridge PhD, MatterGen co-author. Now leads Latent-X pretraining and inference scaling.
05
Henry Kenlay
MTS · July 2024
Oxford DPhil, antibody modelling at Exscientia. Hired seventeen months before the antibody model.
06
Rebecca Bartke-Croughan
Member of Biological Staff · August 2024 · SF
Berkeley PhD in cell biology. The first Member of Biological Staff, and the only early lab hire still there.

A seventh hire, a research engineer from Microsoft Research, joined in October 2024 and went back to Google DeepMind in early 2026; see the departures.

1.3 — What the founder says, and what the roster shows

He says he brought people over from AlphaFold and Gemini. The roster shows two from the AlphaFold team, and no one from Gemini.

— Simon Kohl, CVPR 2026 keynote, June 2026

“I was fortunate to bring others over from the AlphaFold team, from the DeepMind Gemini team, and then many other places across academia and industry.”

Self-report. Six months earlier, in pharmaphorum: “Others from DeepMind have joined.”

— What the roster shows

3
AlphaFold authors, counting an adviser: the founder, hire #1 and an AlphaFold1 co-author who advises on strategy and talent.
0
From the Gemini team. Closest: the Head of AI co-authored TxGemma.
6
With DeepMind anywhere on the CV, counting a contract stint; three of them in operations and talent.
9
Of 19 technical staff have another AI-for-biology company on the CV.

Six of 26 have DeepMind somewhere on the CV. Three build models: the founder, his first hire and the Head of AI, who arrived in May 2026. The other three, the Head of Operations, a strategy-and-operations hire and the talent manager, came out of DeepMind's and Isomorphic's operations and people teams. A third AlphaFold author, an AlphaFold1 co-author, advises on strategy and talent; we could not read his profile. DeepMind supplied the founding pair and the operating layer. The research bench came from somewhere else, and that is the more useful half of the story.

§ 02 — Part two of four · Three models in nine months

Nine people took $50 million. Twelve shipped the first model five months later.

February to December 2025, and the agent in March 2026. The bench is hired from the labs that invented the field, and from the startups in between.

2.1 — The 2025 bench · six hires, five of them modellers

Hired from the two labs that invented the field, AlphaFold's and David Baker's, and from the startups in between.

01
Sebastian Schmon
February 2025 · MTS · from Altos Labs
Oxford DPhil in computational statistics, an assistant professorship at Durham, then senior staff ML engineer at Altos Labs. He arrived the month the company came out of stealth.
02
Daniella Pretorius
April 2025 · Computational Protein Design Lead
Imperial PhD in computational protein design, with research at MIT. The first person whose job title is the product's job, and the workflow Latent-Y was later built to mimic.
03
Simon Mathis
July 2025 · MTS · from the Baker lab
ETH physics, a Cambridge CS PhD, a stint at Absci, then a year in David Baker's lab: co-author on RFdiffusion3 and RF3. Started the month Latent-X shipped.
04
Amir Motmaen
September 2025 · MTS · San Francisco
PhD inside Baker's Institute for Protein Design: peptide-MHC binders in Science, GPCR miniproteins in Nature. Left in December 2025 and rejoined in July 2026. The second Baker-lab hire in three months, placed next to the wet lab.
05
James Vuckovic
October 2025 · MTS · from Dreamfold
Senior ML engineer at Dreamfold, co-author of FoldFlow-2; Microsoft's Turing team before that. Flow matching for protein generation, hired from the startup that published it.

The sixth 2025 hire, an executive assistant, is a credited author on two technical reports. At this size, the author list is the staff list.

2.2 — The cadence · July 2025 to March 2026

Three launches in nine months, from a team that, on our count, never passed seventeen.

July 2025 · 12 peopleLatent-XAll-atom design of protein binders, macrocycles and mini-binders, in a web browser, with lab validation. The first model, two years after incorporation.
December 2025 · 14 peopleLatent-X2Antibodies and peptides with drug-like properties. The turn to antibodies: “Many people told me antibodies were a solved problem… Initially, I didn't focus on them with the company.”
March 2026 · 17 peopleLatent-YAn agent that runs a whole antibody campaign from a text prompt: literature, epitope, design, validation. Lab-confirmed binders on 67% of tested targets. Opened to selected partners; a Research Tier followed in July.

— Simon Kohl, Free Radicals, June 2026

“We have found a recipe that allows us to hill climb rapidly. It requires our own lab, our own models, and our own data collection. It all needs to come together.”

— What Latent sells, in one sentence

Access to its design models and the agent through a web platform, for pharma and biotech partners who keep the drug; Latent builds no pipeline of its own. The lab stays small on purpose: “None of the targets we've gone after we've ever made more than a hundred designs against.”

2.3 — The citation ledger · OpenAlex, verified author records

Two people hold 91% of the citations. The other 24 are the company.

— Share of 146,000 citations summed across the 26, in thousands

Bridgland's 77,000 include 48,000 from AlphaFold2 alone; Kohl's 56,000 are AlphaFold2 and the database; the Head of AI's 9,000 are medical imaging and nnU-Net. Citations measure the past, and here the past is AlphaFold. Strip out the two authors and the Head of AI and the remaining 23 people have about 4,000 citations between them, almost all since 2021: Baker-lab papers in Science and Nature, FutureHouse's agents, MatterGen, FoldFlow-2. The reputation is inherited; the bench's own record is being written in the company's technical reports. That is normal for a three-year-old lab. It is also why hire #1 mattered more than any hire since.

Talent brief

Want the full visual breakdown?

Download the PDF version of this teardown: the headcount chart month by month, the protein-design primer drawn out, the founder and the Head of AI side by side, and five lessons for founders spinning out of a big lab.

§ 03 — Part three of four · The scale year · 2026

Fifteen starts, three departures, and a Head of AI with the founder's CV.

January to October 2026. The company nearly doubles, the hires track the product, and London's DeepMind-alumni market gets crowded.

3.1 — What 2026 hired · fifteen starts in ten months, fourteen still there

Grouped by what they were hired to build, the 2026 hires are the product roadmap.

The platform
A lead web engineer from Apron, ex-Revolut (Feb); applied-AI staff in San Francisco (May) and Cambridge (Jul); a doctor as technical program manager (May). Latent-X went on the web; the people to run a web product followed.
The antibody turn
Ollie Turnbull, a second Oxford OPIG antibody modeller (Jun); Prasanth Kumar, a protein-and-cell engineer from Generate:Biomedicines for the San Francisco bench (Sep). Both after Latent-X2 made antibodies the product.
The agent
Sam Wright, from FutureHouse, then founding MTS at Edison Scientific; co-author of PaperQA and ChemCrow. Hired six months after Latent-Y, from the lab that defined science agents.
More modellers
Sven Over, a physics PhD from Oxford Ionics and Facebook, the bench's first career software engineer (Jan); Akshay Subramanian, an MIT PhD who interned at Generate (Mar, San Francisco); Ward Haddadin, an enzyme-design lead from Xyme (Oct).
The operating layer
An interim Head of Operations and a strategy-and-operations hire from BenevolentAI and Google DeepMind (both Jan); a Talent Acquisition Lead (Mar) who left in September; a Talent & Operations Manager, ex-Isomorphic (Aug). The first year the company staffed its own hiring.
The Head of AI
Paul Jaeger, from Google DeepMind (May). Next section.

3.2 — The Head of AI · May 2026

The Head of AI has the founder's CV, almost line for line.

— Simon Kohl · Founder & CEO · 2023

2010 – 2016
BSc and MSc in physics, Karlsruhe Institute of Technology
2016 – 2019
KIT PhD done at DKFZ Heidelberg, medical image computing; nnU-Net co-author
2017 – 2022
Co-founds the Heidelberg AI meetup
2019 – 2022
DeepMind: AlphaFold2, then starts and co-leads protein design
2023
Founds Latent Labs in London

— Paul Jaeger · Head of AI · May 2026

2010 – 2016
BSc and MSc in physics, Karlsruhe Institute of Technology
2016 – 2020
KIT PhD done at DKFZ Heidelberg, same group; nnU-Net co-author
2017 – 2024
Organizes the Heidelberg AI meetup for seven years
2020 – 2024
Postdoc, then principal investigator at DKFZ: Metrics Reloaded (Nature Methods), an ICLR 2023 oral
2024 – 2026
Senior research scientist at Google DeepMind (TxGemma), then Latent Labs

About 9,400 citations, almost all in medical imaging; he followed the founder's path into DeepMind two years after the founder left it. A startup's most senior technical hire is usually a stranger with a résumé. This one is a nine-year collaborator. The upside is trust at a layer where trust is scarce. The risk is that the two most senior AI people share one lineage, KIT, DKFZ and DeepMind, twice over, in a company that now designs antibodies.

3.3 — The departures · 2026

Three left this year: one back to DeepMind, one from the lab, one to a competitor.

01
Agrin Hilmkil
MTS · October 2024 to early 2026 · → Google DeepMind
From Microsoft Research; a Latent-Y author. Back at Google DeepMind as a research engineer from February: the company the founder left, hiring from the company he built.
02
David Yuan
Head of Screening Platform · March 2024 to March 2026 · → Prellis Biologics
Led the screening platform in the wet lab the founder calls one third of the recipe. Left for Prellis Biologics the month Latent-Y, which he co-authored, was published. The company's team page still lists him; no replacement appears on the roster.
03
Joe Daniels
Talent Acquisition Lead · March to September 2026 · → Basecamp Research
Hired to run the scale year's recruiting; six months later he is Technical Talent Leader at Basecamp Research, a London protein-AI company. The talent function turned over in 2026; an ex-Isomorphic hire arrived in August.

— Also on the record

An interim Head of Operations has sat alongside the founding Head of Operations since January. One more former engineer and three authors whose status we could not confirm are not counted here.

— Why it matters more than three of 26

Three departures in a year is ordinary. Who left is not: the lab's leader, the person hired to hire, a model author returning to the parent. A spinout competes with the lab it left for as long as both exist.

3.4 — Two cities, two jobs

London builds the models. San Francisco is six people, four of them new this year.

20
United Kingdom: 18 in or around London, one each in Oxford and Cambridge. The founder, the Head of AI, the modelling bench, all operations.
6
San Francisco: both biologists and four modellers, placed next to the lab.
4
Of the six in San Francisco started in 2026, two in September.
0
Wet-lab leaders on the roster since March.

“That's why at Latent Labs we have our own wet lab in San Francisco,” the founder told CVPR in June. By his own description the lab is a third of what makes the company work: own lab, own models, own data. On the roster it is two biologists, one of whom started in September, and four modellers, three of whom started this year. Its first leader left in March. The lab can stay small by design, fewer than a hundred designs per target, but the part of the recipe the founder says matters most is the newest and thinnest part of the company.

Watch the San Francisco hires. A lab lead, or a second screening scientist, would say the data loop is being rebuilt. More applied-AI staff would say the platform is winning the argument for headcount.

3.5 — Where the 26 came from · schools, labs and companies anywhere on the CV

Cambridge, Oxford, and nine of nineteen technical staff with another AI-for-biology company on the CV.

SchoolsA Cambridge–Oxford benchSix passed through Cambridge, four through Oxford, two through ETH Zurich. Fifteen of 26 hold a PhD; nineteen joined at a senior stage. Seven trained as physicists first, the founder and the Head of AI among them. The founder's description of the AlphaFold2 team: “a lot of people like me, either computer scientists or physicists.”
The field's own labsTwo from Baker's lab, two from Oxford OPIG, two from AlphaFoldThe groups that invented protein design and antibody modelling each supplied a pair. Add six with DeepMind on the CV, and the lineage is three laboratories. Nobody came from EvolutionaryScale, Xaira or Chai; Isomorphic appears only in people operations.
Competitors and neighboursSenior talent comes from peersExscientia and Generate twice each; Absci, Dreamfold, Altos, Xyme, Infinitopes and FutureHouse once. Nine of nineteen technical staff have another AI-for-biology company on the CV. Since the Series A, about half the modelling hires had done the job somewhere else.
Versus Chai DiscoverySame race, different lineagesChai Discovery, the peer we analyzed in October, has no DeepMind alumni, and its one Baker-lab tie is a founding scientist who was in the lab as a teenager; Latent has no ESM alumni. Nobody has moved between them. The sourcing maps barely overlap, and neither has raided the other yet.

§ 04 — Part four of four · What to make of it

A famous lineage got the first cheque. The next hires come from a pool everyone in London is fishing.

Isomorphic, Inherent, Basecamp and DeepMind itself want the same people. The founder says the roles are open and the space is “really going off”.

4.1 — The market around them · September to October 2026

The roles are open, the founder says, because “this space is really going off”. So is everyone else's.

— Simon Kohl, CVPR 2026 keynote, June 2026

“We have a lot of roles open both in London and San Francisco — member of technical staff roles, applied research roles — that we're trying to fill rapidly because this space is really going off.”

— The bench, and its buyers

Latent built its bench from Cambridge, Oxford, Baker's lab and the competition. Every one of those pools now has a better-funded London buyer than it did a year ago.

Isomorphic LabsDeepMind's own spinout, $2.1B richerThe dominant London buyer of exactly this profile, and where Latent's new talent manager spent three and a half years.
InherentA new London lab, backed by one of Latent's lead investorsFounded by ex-DeepMind staff; out of stealth in May with a $50M seed co-led by Index and Radical Ventures, which co-led Latent's Series A.
Basecamp ResearchAlready hiring from LatentTook the Talent Acquisition Lead in September. In the thirty days to October 6, no Latent employee posted publicly and no peer announced a hire: the market for this talent moves quietly, in London, one profile at a time.

5 — What we learned

Five things worth copying, and a catch.

01 · First hireHire the one who can rebuild the stackOf the whole AlphaFold team, the founder took one engineer: the one on AlphaFold 1, 2 and 3. Two people carried the lineage; the other 24 were hired from outside the founder's AlphaFold circle. Spend the credibility on one rebuilder.
02 · SequenceBuild the lab before the modelA Head of Screening Platform in March 2024 and a biologist in August, sixteen and eleven months before Latent-X. The recipe the founder describes, own lab, own models, own data, was staffed in that order.
03 · SourcingHire from the labs that invented the fieldTwo Baker-lab alumni in three months, two Oxford antibody modellers, and nine of nineteen technical staff with another AI-for-biology company on the CV. The senior bench learned the job somewhere else first.
04 · TimingStaff the pivot before you announce itThe antibody specialist arrived in July 2024; the antibody model shipped in December 2025; the next antibody hires followed the launch. Hire the expert, then let the roadmap catch up.
05 · GeographyRecruit from hubs outside San FranciscoTwenty of 26 sit in the UK: Oxford and Cambridge supplied the bench, Heidelberg the Head of AI. Only the lab and four modellers are in San Francisco. The Bay Area is where the bidding is, not where the talent is trained.
The catchThe reputation is two people's past.91% of citations sit with the founder and hire #1. Three left this year, including the lab's leader and the person hired to hire. More than half the company joined this year. Retention, not sourcing, is the next test.

— The takeaway

The AlphaFold names opened the doors.
Cambridge, Oxford, Baker's lab and the competition filled the room, and the same market is now hiring from it.

Brief
Latent Labs · Talent Brief
Prepared by
Base to Base · Recruiting
Written for
Founders spinning out of a big lab, and investors sizing up AI-for-biology teams

Methodology & limitations

Twenty-six profiles read, and every self-report labelled.

— Sources

  • The LinkedIn profiles of 26 of 27 current Latent Labs staff and three former staff, collected October 6–7, 2026, with latentlabs.com/team. Investors are left out of every count.
  • The Latent-X, Latent-X2 and Latent-Y technical reports (arXiv 2507.19375, 2512.20263, 2603.29727).
  • Four founder appearances: Free Radicals, pharmaphorum, etn. and the CVPR 2026 keynote.
  • OpenAlex citation records with verified author IDs; TechCrunch and Tech.eu for the funding; Sofinnova Partners for the Latent-Y Research Tier; an October 5 X post for Isomorphic's Series B; Tech.eu for Inherent.

— Limitations

  • 26 is what we read, out of 27. One employee appears on the company's team page but has no readable profile.
  • Founder quotes are self-report, and so are the lab-validation figures, which come from the company's own technical reports.
  • Every join count carries survivorship bias. Departed staff never appear on a current roster unless we traced them, so early headcounts are floors.
  • Technical, senior and lineage groupings are our reading of titles and CVs, not an org chart Latent Labs publishes.
  • Citation counts move daily; they are rounded and dated to collection. Teardowns like this are how our searches begin — this one's on us.